At Southeastern Psychiatric Associates (SEPA), we believe knowledge reduces fear. Let’s break down what science actually says about genetics, environment, and depression risk.

If you’ve tried antidepressants and still don’t feel like yourself, you are not alone — and you are not failing. For many individuals in Randolph, Braintree, Milton, and surrounding Massachusetts communities, depression can feel like a long road of medication changes, side effects, and lingering symptoms. When depression doesn’t respond as expected, there is a clinical explanation — and there are evidence-based next steps.